SUCCESSFUL NON-OPERATIVE TREATMENT IN MICROCYSTIC LYMPHATIC MALFORMATION OF THE TONGUE: A CASE REPORT

Nuri Fitriasari*    -  Faculty of Dentistry, Padjadjaran University, Dr. Hasan Sadikin General Hospital, Bandung, Indonesia
Irna Sufiawati    -  Faculty of Dentistry, Padjadjaran University, Dr. Hasan Sadikin General Hospital, Bandung, Indonesia

(*) Corresponding Author
DOI: 10.30659/odj.9.0.1-6

Background: Microcystic lymphatic malformation (MLM) is an abnormal congenital growth of lymphatic vessels. It may occur in any part of the human body, with 75 % cases found in the head and neck, including in oral cavity. This case report aimed to describe a case of MLM in a child who was successfully treated non-operatively with antibiotics and corticosteroid.
Case Report: A 4-year-old child came to Oral Medicine Clinic of Dr. Hasan Sadikin General Hospital, Bandung, with a chief complaint lesions of the tongue since a year ago, accompanied by bleeding in the affected areas but not pain. Patient gave history of recurrent episodes of the symptoms since 7 months old.
Result : Ultrasonography was performed and diagnosis of microcystic lymphatic malformation was established. Systemic oral corticosteroid, antibiotics, and multivitamins were given and the lesions showed significant improvement after 2-weeks treatment.
Conclusion: Therapy of MLM with antibiotics and systemic oral corticosteroid significantly improved patient’s condition, and ultrasonography may be used as a diagnostic modality in MLM diagnosis.

Keywords: Microcystic lymphatic malformation; Ultrasonography; Corticosteroid; Antibiotics

  1. Greene A. Operative Management of Vascular Anomalies. Operative Management of Vascular Anomalies. Rio de Janeiro: Thieme; 2017. 3–109 p.
  2. Richter GT, Friedman AB. Hemangiomas and Vascular Malformations: Current Theory and Management. Int J Pediatr. 2012;2012:1–10.
  3. Freixo C, Ferreira V, Martins J, Almeida R, Caldeira D, Rosa M, et al. Efficacy and safety of sirolimus in the treatment of vascular anomalies: A systematic review. J Vasc Surg. 2020;71(1):318–27.
  4. White CL, Olivieri B, Restrepo R, McKeon B, Pinar Karakas S, Lee EY. Low-flow vascular malformation pitfalls: From clinical examination to practical imaging evaluation - Part 1, lymphatic malformation mimickers. Am J Roentgenol. 2016;206(5):940–51.
  5. Eltohami YI, Alim NE, Abuaffan AH. Microcystic Lymphatic Malformation: A Case Report. Dentistry. 2017;07(03):2–3.
  6. Cheng LH, Lee JC, Kao CH, Shi ZP, Lin YS. Lymphangiomatous macroglossia associated with extensive cervicomediastinal cystic hygromas. J Chinese Med Assoc. 2013;76(11):653–6.
  7. Khanum N, Smitha, Kanwar S. Microcystic Lymphatic Malformation: A Case Report. Dentistry. 2017;07(03):67–70.
  8. Ma J, Biao R, Lou F, Lin K, Gao YQ, Wang ML, et al. Diagnosis and surgical treatment of cervical macrocystic lymphatic malformations in infants. Exp Ther Med. 2017;14(2):1293–8.
  9. Garcia-Montero P, Del Boz J, Sanchez-Martinez M, Santos IME, Baselga E. Microcystic lymphatic malformation successfully treated with topical rapamycin. Pediatrics. 2017;139(5).
  10. Greene AK, Perlyn CA, Alomari AI. Management of lymphatic malformations. Clin Plast Surg. 2011;38(1):75–82.
  11. M JF, Soni HM, Pimpalwar S. Medical management of vascular anomalies. Semin Cutan Med Surg. 2016;35(3):177–81.
  12. Wiegand S, Eivazi B, Zimmermann AP. Microcystic Lymphatic Malformations of the Tongue. Arch Otolaryngol Head Neck Surg. 2011;135(10):976–83.
  13. Kulungowski AM, Patel M. Lymphatic malformations. Natl Organ Rare Disord. 2020;29(5):1–10.
  14. Lerat J, Mounayer C, Scomparin A, Orsel S, Bessede JP, Aubry K. Head and neck lymphatic malformation and treatment: Clinical study of 23 cases. Eur Ann Otorhinolaryngol Head Neck Dis. 2016;133(6):393–6.
  15. Ricci KW. Advances in the medical management of vascular anomalies. Semin Intervent Radiol. 2017;34(7):239–49.
  16. Wiegand S, Wichmann G, DIetz A. Treatment of Lymphatic Malformations with the mTOR Inhibitor Sirolimus: A Systematic Review. Lymphat Res Biol. 2018;16(4):330–9.

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