THE ROLE OF MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS AND STAGING OF ORAL SQUAMOUS CELL CARCINOMA: CASE REPORTS

Rahmi Harmiyati, Irna Sufiawati, Harry Galuh Nugraha

Abstract


Background: Oral Squamous Cell Carcinoma (OSCC) is oral cancer with various clinical presentations. Therefore, to assist in establishing the diagnosis, supporting examinations are needed, one of which is MRI which is non-invasive and harmless to the patient. This case report aims to describe 3 suspected cases of OSCC and the differential diagnosis of chronic traumatic ulcers using Magnetic Resonance Imaging (MRI) to support the diagnosis and staging of OSCC.
Case Report: The first case a 73-years-old woman, complained of canker sores, pain, difficulty chewing since 3 months. Intraoral examination revealed ulcers, irregular, positive induration, 0.5x1cm in size, on the right lateral tongue, tooth region 46. Histopathological examination was performed and the results showed invasion of malignant cells. An MRI was performed with a suspected malignant neoplasm at stage T1N0. The second case, a 45-years-old woman, complained of canker sores on the right tongue, pain and stiffness, since 2 months. Intraoral examination revealed ulcers, irregular, positive induration, size 2x5cm, on the right lateral tongue, tooth region 46-48. On MRI examination, an inhomogeneous solid mass was seen in the right corpus glossus area, accompanied by enlarged lymph nodes. The third case, a 83-years-old woman, complained of canker sores, pain when swallowing, since 3 weeks. Intraoral examination revealed an ulcer, irregular, positive induration, 2mm in size, on therright side of the tongue, in the region of 16 roots. MRI examination showed nodules measuring 9x17mm, suspected inflammatory/infectious lesions accompanied by acute tonsillitis right, less supportive of malignant neoplasms.
Conclusion: Non-invasive MRI plays an important role in establishing a definitive diagnosis and staging OSCC


Keywords


OSCC; Chronic traumatic ulcer; MRI

References


Sirait AM. FAKTOR RISIKO TUMOR/KANKER RONGGA MULUT DAN TENGGOROKAN DI INDONESIA (Analisis Riskesdas 2007). Media Penelit dan Pengemb Kesehat. 2013;23(3):122-9.

Subapriya R, Thangavelu A, Mathavan B, Ramachandran CR, Nagini S. Assessment of risk factors for oral squamous cell carcinoma in Chidambaram, southern India: A case-control study. Eur J Cancer Prev. 2007;16(3):251–6.

Bagan J, Sarrion G, Jimenez Y. Oral cancer: Clinical features. Oral Oncol.2010;46(6):414–7.

Laimer J, Lauinger A, Steinmassl O, Offermanns V, Grams AE, Zelger B, et al. Cervical lymph node metastases in oral squamous cell carcinoma-how much imaging do we need? Diagnostics. 2020;10(4):1–9.

Fedele S. Diagnostic aids in the screening of oral cancer. Head Neck Oncol. 2009;1:5.

Sarrión Pérez MG, Bagán J V., Jiménez Y, Margaix M, Marzal C. Utility of imaging techniques in the diagnosis of oral cancer. J Cranio-Maxillofacial Surg.2015;43(9):1880–94

Arya S, Chaukar D, Pai P. Imaging in oral cancers. Indian J Radiol Imaging. 2012;22(3):195–208.

Whaites E, Drage N. essentials of dental radiography and radiology. 5th ed. Whaites E, Drage N, editors. London: Churchill Livingstone Elsevier; 2013.

White S, Pharoah M. Oral Radiology: Principles and Interpretation. 7th ed. White S, Pharoah M, editors. St.Louis, Missouri: Elsevier Mosby; 2014.

Linz C, Müller-Richter UDA, Buck AK, Mottok A, Ritter C, Schneider P, et al. Performance of cone beam computed tomography in comparison to conventional imaging techniques for the detection of bone invasion in oral cancer. Int J Oral Maxillofac Surg. 2015;44(1):8–15.

Lam P, Au-Yeung KM, Cheng PW, Wei WI, Yuen APW, Trendell-Smith N, et al. Correlating MRI and Histologic Tumor Thickness in the Assessment of Oral Tongue Cancer. Am J Roentgenol. 2004;182(3):803–8.

Lodder WL, Teertstra HJ, Tan IB, Pameijer FA, Smeele LE, Van Velthuysen MLF, et al. Tumour thickness in oral cancer using an intra-oral ultrasound probe. Eur Radiol. 2011;21(1):98–106.

De Paiva RR, de Souza Figueiredo PT, Leite AF, Silva MAG, Guerra ENS. Oral cancer staging established by magnetic resonance imaging. Braz Oral Res. 2011;25(6):512–8

Rumboldt Z, Day TA, Michel M. Imaging of oral cavity cancer. Oral Oncol. 2006;42(9):854–65.

Ansarin M, Bruschini R, Navach V, Giugliano G, Calabrese L, Chiesa F, et al. Classification of GLOSSECTOMIES: Proposal for tongue cancer resections. Head Neck. 2019;41(3):821–7.




DOI: http://dx.doi.org/10.30659/odj.9.0.24-32

Refbacks

  • There are currently no refbacks.


Lisensi Creative Commons
This work is licensed under a Lisensi Creative Commons Atribusi-BerbagiSerupa 4.0 Internasional.
Contact us: ODONTO Dental Journal: Jl. Raya Kaligawe Km.4, PO BOX 1054/SM Semarang, Central Java, Indonesia, 50112. Email: odontodentaljournal@unissula.ac.id