Irritation, Hedonic, and Activity Tests of Nanoserum Extract of Red Shoot Leaves (Syzigium myrtifolium Walp) as a UV Ray Blocker

Uce Lestari, Fathnur Sani, Yuliana Yuliana, Luri Mekeama

Abstract


(1) Background: Red shoot leaf extract (Syzigium myrtifolium Walp) contains bioactive compounds such as flavonoids, tannins, and anthocyanins that have the potential to act as anti-oxidants and protect the skin from UV exposure. This study aims to test the irritation, hedonic level, and the activity of red shoot leaf extract nanoserum as an ultraviolet (UV) ray blocker before and after use; (2) Methods: The process of making na-noserum is carried out through the ionic gelation method using chitosan and alginate polymers with HPMC serum carriers. The manu-facture of red shoot leaf extract nanoparticles is intended to increase the stability, absorption, and effectiveness of the active ingredients. The irritation test was carried out on 20 people on the skin of volunteers to ensure safety of use, while the hedonic test involved panelists to assess the aspects of color, aroma, texture, and comfort of use. The UV ray blocker activity test was carried out using a Sunscreen UV Mirror (UV Camera Built in). (3) Results: Nanoserum red shoot leaf extract did not cause skin irritation by 100%, was liked by most panelists by 90% (color, aroma, texture, and comfort), and had a very high protective category against UV radiation by 100%; (4) Conclusions: Nanoserum red shoot leaf extract with a concentration of 0.28% is a natural cosmetic product that is safe, widely liked, and has high protection in protecting the skin from damage due to exposure to ultraviolet rays

Full Text:

PDF

References


Nasela, T; Lestari, U; Asra, R (2025). Clinical evaluation of dragon’s blood sunscreen (Daemonorops draco (Willd.) Blume) as an antioxidant and ultraviolet (UV) protector. Riset Informasi Kesehatan, 14 (2) hal 269-275.

Lestari, U; Muhaimin, M; Maimum, M; Yuliana, Y (2024). Formulation of Soothing Gel Ethanol Extract of Red Shoot Leaves (Syzigium myrtifolium. Walp) as an Antioxidant. Riset Informasi Kesehatan, 14(1), 138-146.

Sahu, A. N (2013). Nanotechnology in herbal medicines and cosmetics. International Journal of Research in Ayurveda and Pharmacy, 472-474.

Vaiserman, A.; Alexander, K.; Alexander, Z.; Alina, L (2020). Nanodelivery of Natural Antioxidants: An Anti-aging Perspective. Front. Bioeng. Biotechnol. 7, 447.

Sindhu, R. K., Gupta, R., Wadhera, G., & Kumar, P (2022). Modern Herbal Nanogels:Formulation, Delivery Methods, and Applications. Gels, 8(2), 1–23. https://doi.org/10.3390/gels8020097

Az-Zahra, Ajeng Aprina; Asra, Revis; Lestari, Uce, 2025. Formulation and stability testing of physical properties of sun-screen from Dragon's Blood Resin (Daemonorops draco (Willd.) Blume), Riset Informasi Kesehatan, 14(2), 348-356

Lestari U, Faizar F, Yuliawati, Septa P (2021) Irritation Test And Effectiveness of Facial Humidity Skin From Peel Off Gel Mask Based of Date Palm Seeds Powder (Phoenix dactylifera). Journal BIGME, 1,2, 1-5.

Lestari U, Syamsurizal S, Faizar F. (2021). Irritation Test and Effectiveness of The Clean Power Activated Charcoal Palm Shells (Elaeis guineensis Jacg) as Adsorbent Dirt on The Hair. Indonesian Journal of Pharmaceutical Research (IJPR), 1(1), 13-18.

Monic, S.C; Muhaimin, M; Yuliawati Y; U, Lestari; Fathnur S, K. (2022). Formulasi, Uji Efektivitas dan Uji Hedonik Masker Gel Peel Off Kombinasi Ekstrak Rimpang Kunyit (Curcuma longa L.) dan Madu (Mel depuratum) Sebagai Peningkat Elastisitas Kulit, Medical Sains : Jurnal Ilmiah Kefarmasian, 7, 2, hal 23-26.

Lestari U, Ulan S, Madyawati L (2020). Uji Iritasi Dan Efektifitas Spray Handsanitizer Ekstrak Etanol Daun Jeruju (Achantus Ilicifolious) Sebagai Antibakteri. JMJ, Special Issues, JAMHESIC 2020, Hal: 34-39

Yokobeth AJL, Lestari U, Muhaimin M (2021). Uji Iritasi Dan Efektifitas Masker Gel Peel Off Arang Aktif Cangkang Sawit (Elaeis guinensis Jacq) Sebagai Pembersih Wajah. Indonesian Journal of Pharma Science. 1 (1), Hal.28-41.

Lestari, Uce; Muhaimin, Muhaimin; Yuliana, Yuliana; Mekeama, Luri. 2025. Uji Iritasi dan Hedonik Masker Gel Je-rawat yang Mengandung Minyak Jinten Hitam (Nigella sativa Linn) dan Minyak Zaitun (Olea europaea var. Europea), Jurnal Farmasi Udayana, 14 (1) hal 17-21.

Lestari U, Riki S, Andy B, Eza PS, Eugenia G, Lismiati, Erin A (2021). Aplikasi Dan Uji Klinis Arkawa Black Soap Pada Pelaku Usaha Mikro Kecil Dan Menengah Kabupaten Tanjab Timur. Jurnal Karya Abdi. 5, 3, 400-406.

Fitria M, Ni Luh K.A.A.D, Ni Putu, D.A, Ni Made SD. (2024). Survey Penerimaan Konsumen dan Uji Iritasi terhadap Sediaan Gel Masker Peel-Off Batang Pisang (Musa paradisiaca L.) dan Bunga Widuri (Calotropis gigantea L.). Jurnal Ilmiah Medicamento. 10(1):1-9.

Lestari, U; Muhaimin, M; Chaerunisaa, A.Y; Sujarwo, W. 2023. Improved Solubility and Activity of Natural Product in Nanohydrogel. Pharmaceuticals, 16, 1701.

Lestari U, Putri Z W, Muhaimin. (2022). Uji Efektifitas Dan Iritasi Masker Gel Peel Off Arang Aktif Cangkang Nipah (Nypa fruticans Wurmb.) Sebagai Pembersih Wajah. Indonesian Journal of Pharma Science (IJPS). 4, 2, 167-178.

Lestari U, Riki S, Andy B, Eza PS, Eugenia G, Lismiati, Erin A. (2021). Uji Klinis Produk Arkawa Black Soap Pada 50 Orang Volunteer di PT. Sumbertama Nusa Pertiwi, Sungai Gelam, Muaro Jambi. Prosiding Seminar Nasional Hasil Penelitian dan Pengabdian Masyarakat.

Adawiyah, D.R., Fidrianny, I., & Rizal, M.Y. (2019). Uji Aktivitas Antioksidan Ekstrak Daun Pucuk Merah (Syzygium oleana) Terhadap Radikal Bebas 1,1-Diphenyl-2-Picrylhydrazyl (DPPH). Jurnal Farmasi dan Ilmu Kefarmasian Indo-nesia, 6(1), 1-5.

Aryani, A., & Sumarno, S. (2018). Aktivitas Antioksidan Ekstrak Etanol Daun Pucuk Merah (Syzygium oleana) pada Berbagai Jenis Pelarut. Jurnal Sains Farmasi & Klinis, 5(2), 89-94.

Setiawan, D., & Suhendra, A. (2017). Uji Aktivitas Antioksidan Ekstrak Daun Pucuk Merah (Syzygium oleana) dengan Metode 2,2-Difenil-1-Pikrilhidrazil (DPPH). Jurnal Teknologi dan Industri Pangan, 28(1), 35-41.

Lestari, U; Muhaimin, M; Chaerunisaa, A.Y; Sujarwo, W (2025). Formulation Development of Natural Polymeric Nano-particles, In Vitro Antiaging Evaluation, and Metabolite Profiling of Toona sinensis Leaf Extracts. Pharmaceuticals, 18(3), 288.

Bahar, Yadela; Lestari, Uce. 2021 Penentuan nilai sun protection factor (SPF) ekstrak etanol daun jeruju (acanthus Ilicifo-lius l.) secara in vitro, Indonesian Journal of Pharma Science, 3(2) hal 91-96

Lismiati, Lismiati; Lestari, Uce; Syamsurizal, Syamsurizal, 2021. Uji Sifat Fisikokimia Sediaan Sunscreen Fraksionat Ekstrak Diklorometan Kulit Buah Artocarpus Altilis, Jurnal Farmasetis, 10(2) hal 123-134

Lestari U, R Asra, Yusnelti, 2023. Development of Jernang Non-timber Forest Product in the Bukit Dua Belas National Park Area Jambi can be Jernang (Daemonorops draco(Willd.) Blume ) Sunscreen With SPF 15, DEMETER: Journal of Farming and Agriculture, 1 (issue 1) hal 30-35

Lestari, Uce; Asra, Revis; Yusnelti, Yusnelti. 2020. Formulation and Characterisation of Jernang Resin (Daemonorops draco (Willd.) Blume) Sunscreen Creams. Journal of Pharmacy & Bioallied Sciences, 12.

Pratiwi, Puspa Dwi; Yuliawati, Yuliawati; Lestari, Uce,2023. Penentuan penangkal radikal dan sun protection factor krim kombinasi ekstrak etanol kunyit dan temu putih, Journal of Pharmaceutical and Sciences, hal 240-245.


Refbacks

  • There are currently no refbacks.