Medical Faculty, Diponegoro University
Post-Therapy Thrombocytopenia in Nasopharyngeal Carcinoma: Radiotherapy vs Chemoradiotherapy
Keywords: Nasopharyngeal Carcinoma Radiotherapy Chemoradiotherapy Thrombocytopenia
- Adham, M., Kurniawan, A. N., Muhtadi, A. I., Roezin, A., Hermani, B., Gondhowiardjo, S., Tan, I. B., & Middeldorp, J. M. (2012). Nasopharyngeal carcinoma in Indonesia: epidemiology, incidence, signs, and symptoms at presentation. Chinese journal of cancer, 31(4), 185–196. https://doi.org/10.5732/cjc.011.10328
- Al-Azri M. H. (2016). Delay in Cancer Diagnosis: Causes and Possible Solutions. Oman medical journal, 31(5), 325–326. https://doi.org/10.5001/omj.2016.65
- Asnir, R. A., Yudhistira, A., & Friliandita, N. (2020). Profile of nasopharyngeal cancer patients in Otorhinolaryngology - HNS Department Haji Adam Malik General Hospital Medan during 2014 - 2016. International Journal of Nasopharyngeal Carcinoma, 2(3), 79–81.
- Audina, N. T., Yusmawan, W., Naftali, Z., & Suprihati, S. (2019). Perbandingan kejadian leukopenia dan trombositopenia pada pendertia karsinoma nasofaring yang mendapatkan kemoterapi paclitaxel cisplatin dan cisplatin 5-fluorouracil (5-FU). Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal), 8(4), 1187-1196. https://doi.org/10.14710/dmj.v8i4.25355
- Bagby, G. (2004). Leucopenia and leucocytosis. In Cecil Textbook of Medicine (22nd ed., pp. 9–98). Philadelphia, PA: Saunders.
- Barabas, K., Milner, R., Lurie, D., & Adin, C. (2008). Cisplatin: a review of toxicities and therapeutic applications. Veterinary and comparative oncology, 6(1), 1–18. https://doi.org/10.1111/j.1476-5829.2007.00142.x
- Chang, E. T., Ye, W., Zeng, Y. X., & Adami, H. O. (2021). The Evolving Epidemiology of Nasopharyngeal Carcinoma. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 30(6), 1035–1047. https://doi.org/10.1158/1055-9965.EPI-20-1702
- Fauzan, A., Susilawati, S., & Larasati, V. (2022). The association between clinical characteristics and histopathology of nasopharyngeal carcinoma at Dr. Mohammad Hoesin General Hospital, in 2019-2020. Biomedical Journal of Indonesia, 8(1), 13–19. https://doi.org/10.32539/BJI.v8i1.133
- Gao, A., Zhang, L., & Zhong, D. (2023). Chemotherapy-induced thrombocytopenia: literature review. Discover. Oncology, 14(1), 10. https://doi.org/10.1007/s12672-023-00616-3
- Hu, J., Tang, L., Cheng, Y., Liu, A., & Huang, L. (2022). Risk Analysis of Severe Thrombocytopenia in Nasopharyngeal Carcinoma During Concurrent Radio-Chemotherapy. Frontiers in oncology, 11, 754624. https://doi.org/10.3389/fonc.2021.754624
- International Agency for Research on Cancer. (2020). Age standardized (World) incidence rates, nasopharynx, males, all ages in Indonesia. World Health Organization. Retrieved February 28, 2023, from https://gco.iarc.fr/today/en/
- Jicman Stan, D., Niculet, E., Lungu, M., Onisor, C., Rebegea, L., Vesa, D., Bezman, L., Bujoreanu, F. C., Sarbu, M. I., Mihailov, R., Fotea, S., & Tatu, A. L. (2022). Nasopharyngeal carcinoma: A new synthesis of literature data (Review). Experimental and therapeutic medicine, 23(2), 136. https://doi.org/10.3892/etm.2021.11059
- Jinna, S., & Khandhar, P. B. (2023). Thrombocytopenia. In StatPearls [Internet]. Treasure Island, FL: StatPearls Publishing. Updated July 4, 2023. Available from https://www.ncbi.nlm.nih.gov/books/NBK542208/
- Kumar, S., Mahdi, H., Bryant, C., Shah, J. P., Garg, G., & Munkarah, A. (2010). Clinical trials and progress with paclitaxel in ovarian cancer. International journal of women's health, 2, 411–427. https://doi.org/10.2147/IJWH.S7012
- Rallis, K. S., Lai Yau, T. H., & Sideris, M. (2021). Chemoradiotherapy in Cancer Treatment: Rationale and Clinical Applications. Anticancer research, 41(1), 1–7. https://doi.org/10.21873/anticanres.14746
- Reffai, A., Mesmoudi, M., Derkaoui, T., Ghailani Nourouti, N., Barakat, A., Sellal, N., Mallick, P., & Bennani Mechita, M. (2021). Epidemiological Profile and Clinicopathological, Therapeutic, and Prognostic Characteristics of Nasopharyngeal Carcinoma in Northern Morocco. Cancer control : journal of the Moffitt Cancer Center, 28, 10732748211050587. https://doi.org/10.1177/10732748211050587
- Romdhoni, A. C., Alkaff, F. F., Kahdina, M., et al. (2020). Radiotherapy effect on complete blood count parameter in patients with nasopharyngeal carcinoma. International Journal of Nasopharyngeal Carcinoma, 2(2), 7-9.
- Shah, A. B., & Nagalli, S. (2022). Nasopharyngeal carcinoma. In StatPearls [Internet]. Treasure Island, FL: StatPearls Publishing. Updated October 1, 2022. Available from https://www.ncbi.nlm.nih.gov/books/NBK554588/
- Shah, J., Patel, S., Singh, B., & Wong, R. (2020). Jatin Shah’s head and neck surgery and oncology (5th ed.). China: Elsevier.
- Shao, L., Luo, Y., & Zhou, D. (2014). Hematopoietic stem cell injury induced by ionizing radiation. Antioxidants & redox signaling, 20(9), 1447–1462. https://doi.org/10.1089/ars.2013.5635
- Sharif, S. E. T., Zawawi, N., Yajid, A. I., Md Shukri, N., & Mohamad, I. (2020). Pathology classification of nasopharyngeal carcinoma. In B. Abdullah, A. Balasubramanian, & N. M. Lazim (Eds.), An evidence-based approach to the management of nasopharyngeal cancer (pp. 73-92). Academic Press. https://doi.org/10.1016/B978-0-12-814403-9.00005-7
- Sinha, S., Winters, R., & Gajra, A. (2024). Nasopharyngeal cancer. In StatPearls [Internet]. Treasure Island, FL: StatPearls Publishing. Updated February 3, 2024. Available from https://www.ncbi.nlm.nih.gov/books/NBK459256/
- Susetiyo, K. A., Kusumastuti, E. H., Yusuf, M., & Falerina, R. (2022). Clinicopathological profile of nasopharyngeal carcinoma in 2016-2019 at Dr. Soetomo General Hospital. ORLI, 52(1), 7-12. https://doi.org/10.32637/orli.v52i1.474
- Tan, C. K., Beh, S. P., Lee, R. Y., et al. (2018). Gender differences in risk of developing nasopharyngeal cancer (NPC) in one of the highest NPC ethnic in the world. Annals of Oncology, 29, 98. https://doi.org/10.1093/annonc/mdy438.016
- Tito Apreza, R., & Gondhowiardjo, S. A. (2021). The effect of bone radiation on hematopoiesis: A literature review. Journal of the Indonesian Radiation Oncology Society, 12, 62-69.
- Widiastuti. (2019). Karsinoma nasofaring: Kadar Bcl-2, CD44 dan VEGF (1st ed.). Surakarta: UNS Press.
- Wu, L., Li, C., & Pan, L. (2018). Nasopharyngeal carcinoma: A review of current updates. Experimental and therapeutic medicine, 15(4), 3687–3692. https://doi.org/10.3892/etm.2018.5878
- Yao, J. J., Lin, L., Gao, T. S., Zhang, W. J., Lawrence, W. R., Ma, J., & Sun, Y. (2021). Development and Validation of Web-Based Nomograms to Precisely Predict Survival Outcomes of Non-metastatic Nasopharyngeal Carcinoma in an Endemic Area. Cancer research and treatment, 53(3), 657–670. https://doi.org/10.4143/crt.2020.899
- Yu, H., Yin, X., Mao, Y., Chen, M., Tang, Q., & Yan, S. (2022). The global burden of nasopharyngeal carcinoma from 2009 to 2019: an observational study based on the Global Burden of Disease Study 2019. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 279(3), 1519–1533. https://doi.org/10.1007/s00405-021-06922-2
- Zulkarnain, I., Surarso, B., & Purnami, N. (2017). Penurunan hemoglobin, neutrofil, dan trombosit pascakemoterapi cisplatin-paclitaxel pada penderita tumor ganas kepala dan leher. Jurnal THT-KL, 10, 1-10.
Copyright (c) Sains Medika : Jurnal Kedokteran dan Kesehatan

This work is licensed under a Creative Commons Attribution 4.0 International License.
