Corneal edema after cataract surgery in diabetic and non-diabetic patients

Authors

DOI: https://doi.org/10.30659/sainsmed.v15i1.34177
Keywords: Type 2 Diabetes Mellitus, phacoemulsification, corneal edema

Abstract

Patients with diabetes mellitus undergoing phacoemulsification cataract surgery face an elevated risk of corneal edema, primarily due to metabolic disturbances that impair endothelial cell function, leading to delayed post-operative recovery. This prospective cohort study aimed to examine the relationship between diabetes mellitus and the incidence of corneal edema following phacoemulsification. A total of 180 cataract patients scheduled for surgery at Sultan Agung Eye Center, Semarang, and Dr. R. Soedjati Soemodiardjo Regional Public Hospital, Purwodadi, Indonesia, between July and August 2023, were enrolled. Participants were divided into two groups based on the presence or absence of diabetes mellitus. Corneal edema and visual acuity were evaluated on post-operative days 1 and 7. Statistical analyses assessed the association between diabetes mellitus and post-operative corneal edema, with a significance threshold set at p < 0.05. The results indicated that pre-operative visual impairment was significantly worse in non-diabetic patients compared to diabetic patients (p = 0.000). However, post-operative visual improvement was significantly greater in non-diabetic patients on both day 1 (p = 0.02) and day 7 (p = 0.00) compared to diabetic patients. Additionally, the incidence of corneal edema was significantly higher among diabetic patients on both day 1 (p = 0.004) and day 7 (p = 0.001) post-surgery. These findings suggest that diabetes mellitus is associated with a higher risk of corneal edema and delayed visual recovery following phacoemulsification cataract surgery.

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Author Biographies

  • Christina Indrajati, Sultan Agung Islamic University
    Opthalmology Department, Faculty of Medicine, Universitas Islam Sultan Agung
  • Atik Rahmawati, Sultan Agung Islamic University
    Opthalmology Department, Faculty of Medicine, Universitas Islam Sultan Agung

How to Cite

Indrajati, C., Rahmawati, A., & Mahardika, N. A. (2024). Corneal edema after cataract surgery in diabetic and non-diabetic patients. Sains Medika: Jurnal Kedokteran Dan Kesehatan, 15(1), 28-33. https://doi.org/10.30659/sainsmed.v15i1.34177

References

Briceno-Lopez, C., Burguera-Giménez, N., García-Domene, M.C., Díez-Ajenjo, M.A., Peris-Martínez, C., Luque, M.J., 2023. Corneal edema after cataract surgery. J. Clin. Med. 12, 1–17. https://doi.org/10.3390/jcm12216751

Costagliola, C., Romano, V., Forbice, E., Angi, M., Pascotto, A., Boccia, T., Semeraro, F., 2013. Corneal oedema and its medical treatment. Clin. Exp. Optom. 96, 529–535. https://doi.org/10.1111/cxo.12060

Direktorat Jenderal Pencegahan dan Pengendalian Penyakit, 2018. Peta jalan penanggulangan gangguan penglihatan di Indonesia tahun 2017-2030, 2018.

Kausar, A., Farooq, S., Akhter, W., Akhtar, N., 2015. Transient Corneal Edema After Phacoemulsification. J. Coll. Physicians Surg. 25, 505–509.

Kemenkes, R., 2018. Infodatin Situasi Gangguan Penglihatan. Kementrian Kesehat. RI Pus. Data dan Inf. 11.

Kementrian kesehatan, 2021. Infodatin: tetap produktif, cegah dan atasi diabetes melitus. Kementeri. Kesehat.

Kementrian kesehatan, 2018. Keputusan Menteri Kesehatan Indonesia Nomor HK.01.07/MENKES/557/2018 Tentang Pedoman Nasional

Pelayanan Kedokteran Tata Laksana Katarak Pada Dewasa.

Khalid, M., Hanif, M.K., Islam, Q.U., Mehboob, M.A., 2019. Change in corneal endothelial cell density after phacoemulsification in patients with type ii diabetes mellitus. Pakistan J. Med. Sci. 35, 1366–1369. https://doi.org/10.12669/pjms.35.5.596

Kiziltoprak, H., Tekin, K., Inanc, M., Goker, Y.S., 2019. Cataract in diabetes mellitus. World J. Diabetes 10, 140–153. https://doi.org/10.4239/wjd.v10.i3.140

Lundström, M., Barry, P., Henry, Y., Rosen, P., Stenevi, U., 2012. Evidence-based guidelines for cataract surgery: guidelines based on data in the European Registry of quality outcomes for cataract and refractive surgery database. J. Cataract Refract. Surg. https://doi.org/10.1016/j.jcrs.2012.03.006

Sekelj, S., Milec, M.L., Pernar, S.K., Sekelj, A., Farena, S., 2021. Corneal edema recovery after phacoemulsification in type 2 diabetic versus non-diabetic patients. Clin. Diabetol. 10, 144–148. https://doi.org/10.5603/DK.A2021.0003

Shakya, K., Pokharel, S., Karki, K.J.D., Pradhananga, C., Pokharel, R.P., Malla, O.K., 2013. Corneal edema after phacoemulsification surgery in patients with type II diabetes mellitus. Nepal J. Ophthalmol. 5, 230–234. https://doi.org/10.3126/nepjoph.v5i2.8734

Sweitzer, B., Rajan, N., Schell, D., Gayer, S., Eckert, S., Joshi, G.P., 2021. Preoperative Care for Cataract Surgery: The Society for Ambulatory Anesthesia Position Statement. Anesth. Analg. 133, 1431–1436. https://doi.org/10.1213/ANE.0000000000005652

Tang, Y., Chen, X., Zhang, X., Tang, Q., Liu, S., Yao, K., 2017. Clinical evaluation of corneal changes after phacoemulsification in diabetic and non-diabetic cataract patients, a systematic review and meta-analysis. Sci. Rep. 7, 1–16. https://doi.org/10.1038/s41598-017-14656-7

Yang, Y., Chai, H., Ding, Z., Tang, C., Liang, Y., Li, Y., Liang, H., 2023. Meta-analysis of corneal endothelial changes after phacoemulsification in diabetic and non-diabetic patients. BMC Ophthalmol. 23, 1–14. https://doi.org/10.1186/s12886-023-02924-2