Corneal oedema after cataract surgery in diabetic and non-diabetic patients

Christina Indrajati  -  Opthalmology Department, Faculty of Medicine, Universitas Islam Sultan Agung, Indonesia
Atik Rahmawati  -  Opthalmology Department, Faculty of Medicine, Universitas Islam Sultan Agung, Indonesia
Nabila Ayu Mahardika*  -  Faculty of Medicine, Universitas Islam Sultan Agung, Indonesia

(*) Corresponding Author
DOI: 10.30659/sainsmed.v15i1.34177

Introduction: Patients undergoing cataract phacoemulsification surgery with comorbid diabetes mellitus are more susceptible to corneal oedema due to metabolic disorders that disrupt endothelial homeostasis. Corneal oedema is a common complication that occurs after phacoemulsification surgery. The presence of DM comorbidity is expected to prolong the recovery period for corneal oedema. Objective: To determine the relationship between DM and corneal oedema after phacoemulsification surgery.

Methods: A prospective cohort study with 180 samples was obtained using consecutive sampling techniques at RSI Sultan Agung Semarang and RSUD Dr. R. Soedjati Soemodiardjo Purwodadi from July 2023 to August 2023. The sample was divided into two research groups, the control group, and the DM group. Corneal oedema examination and sharp examination were carried out on the first day (D1) and the seventh day (D7) after phacoemulsification surgery. The relationship between variables is explained using a comparative test, the results are considered significant if p<0.05.

Results: The preoperative visual acuity in the non-DM group was significantly more severe than in the DM group (p=0.000). Post-operative visual acuity improved significantly in the non-DM group at post-operative D1 (p=0.02) and D7 (p=0.00) compared to the DM group. The degree of postoperative corneal oedema was significantly more severe in the DM group at post-operative D1 (p=0.004) and D7 (p=0.001) compared to the non-DM group.

Conclusion: Corneal oedema after phacoemulsification surgery accompanied by impaired visual improvement occurs more often in patients with DM risk factors compared to non-DM patients.

Keywords: Diabetes mellitus, phacoemulsification, corneal oedema

Keywords: corneal oedema; diabetes mellitus, phacoemulsification

  1. Briceno-Lopez, C., Burguera-Giménez, N., García-Domene, M.C., Díez-Ajenjo, M.A., Peris-Martínez, C., Luque, M.J., 2023. Corneal edema after cataract surgery. J. Clin. Med. 12, 1–17. https://doi.org/10.3390/jcm12216751
  2. Costagliola, C., Romano, V., Forbice, E., Angi, M., Pascotto, A., Boccia, T., Semeraro, F., 2013. Corneal oedema and its medical treatment. Clin. Exp. Optom. 96, 529–535. https://doi.org/10.1111/cxo.12060
  3. Direktorat Jenderal Pencegahan dan Pengendalian Penyakit, 2018. Peta jalan penanggulangan gangguan penglihatan di Indonesia tahun 2017-2030, 2018.
  4. Kausar, A., Farooq, S., Akhter, W., Akhtar, N., 2015. Transient Corneal Edema After Phacoemulsification. J. Coll. Physicians Surg. 25, 505–509.
  5. Kemenkes, R., 2018. Infodatin Situasi Gangguan Penglihatan. Kementrian Kesehat. RI Pus. Data dan Inf. 11.
  6. Kementrian kesehatan, 2021. Infodatin: tetap produktif, cegah dan atasi diabetes melitus. Kementeri. Kesehat.
  7. Kementrian kesehatan, 2018. Keputusan Menteri Kesehatan Indonesia Nomor HK.01.07/MENKES/557/2018 Tentang Pedoman Nasional
  8. Pelayanan Kedokteran Tata Laksana Katarak Pada Dewasa.
  9. Khalid, M., Hanif, M.K., Islam, Q.U., Mehboob, M.A., 2019. Change in corneal endothelial cell density after phacoemulsification in patients with type ii diabetes mellitus. Pakistan J. Med. Sci. 35, 1366–1369. https://doi.org/10.12669/pjms.35.5.596
  10. Kiziltoprak, H., Tekin, K., Inanc, M., Goker, Y.S., 2019. Cataract in diabetes mellitus. World J. Diabetes 10, 140–153. https://doi.org/10.4239/wjd.v10.i3.140
  11. Lundström, M., Barry, P., Henry, Y., Rosen, P., Stenevi, U., 2012. Evidence-based guidelines for cataract surgery: guidelines based on data in the European Registry of quality outcomes for cataract and refractive surgery database. J. Cataract Refract. Surg. https://doi.org/10.1016/j.jcrs.2012.03.006
  12. Sekelj, S., Milec, M.L., Pernar, S.K., Sekelj, A., Farena, S., 2021. Corneal edema recovery after phacoemulsification in type 2 diabetic versus non-diabetic patients. Clin. Diabetol. 10, 144–148. https://doi.org/10.5603/DK.A2021.0003
  13. Shakya, K., Pokharel, S., Karki, K.J.D., Pradhananga, C., Pokharel, R.P., Malla, O.K., 2013. Corneal edema after phacoemulsification surgery in patients with type II diabetes mellitus. Nepal J. Ophthalmol. 5, 230–234. https://doi.org/10.3126/nepjoph.v5i2.8734
  14. Sweitzer, B., Rajan, N., Schell, D., Gayer, S., Eckert, S., Joshi, G.P., 2021. Preoperative Care for Cataract Surgery: The Society for Ambulatory Anesthesia Position Statement. Anesth. Analg. 133, 1431–1436. https://doi.org/10.1213/ANE.0000000000005652
  15. Tang, Y., Chen, X., Zhang, X., Tang, Q., Liu, S., Yao, K., 2017. Clinical evaluation of corneal changes after phacoemulsification in diabetic and non-diabetic cataract patients, a systematic review and meta-analysis. Sci. Rep. 7, 1–16. https://doi.org/10.1038/s41598-017-14656-7
  16. Yang, Y., Chai, H., Ding, Z., Tang, C., Liang, Y., Li, Y., Liang, H., 2023. Meta-analysis of corneal endothelial changes after phacoemulsification in diabetic and non-diabetic patients. BMC Ophthalmol. 23, 1–14. https://doi.org/10.1186/s12886-023-02924-2

Open Access Copyright (c) 2024 Sains Medika : Jurnal Kedokteran dan Kesehatan
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Sains Medika: Jurnal Kedokteran dan Kesehatan
is published by Faculty of Medicine Universitas Islam Sultan Agung, Indonesia in association with FOKI (FORUM KEDOKTERAN ISLAM INDONESIA).

Contact: Jl. Raya Kaligawe Km.4, PO BOX 1054/SM Semarang 50112, Indonesia
Phone: +62 8122-9933-369
Website: https://fkunissula.ac.id
Email: sainsmedika@unissula.ac.id

ISSN: 2339-093X (Online) | 2085-1545 (Print)
DOI : 10.30659/sainsmed

This work is licensed under a Creative Commons Attribution 4.0 International License

Get a feed by atom here, RRS2 here and OAI Links here

apps