The effect of lifestyle modification on metabolic, anthropometric parameters and hirsutism score in polycystic ovary syndrome
DOI:
https://doi.org/10.30659/sainsmed.v13i2.29137Keywords:
Polycystic Ovary Syndrome (PCOS), fasting blood sugar, triglycerides, high density lipoprotein, hirsutism scoreAbstract
Polycystic ovary syndrome (PCOS) is a hormonal disorder that affects women of reproductive age. It is characterised by several clinical signs and symptoms, including hyperandrogenism, ovarian dysfunction, and chronic anovulation. Obesity and hormonal imbalances can be reduced in PCOS by modifying lifestyle habits. The effects of lifestyle changes on PCOS were investigated, and it was found that consuming less fat and engaging in physical activity reduced metabolic disturbances. The purpose of this study was to examine the effects of lifestyle modifications on metabolic parameters, anthropometric parameters, and the hirsutism score as they relate to the pathogenesis of PCOS. This study involved a total of 10 patients diagnosed with PCOS at the Sultan Agung Semarang Islamic Hospital. Blood glucose, triglycerides, HDL (high density lipoprotein), blood pressure, waist circumference, hirsutism score, and vital sign data related to PCOS were measured before and after a 4-month treatment. PCOS patients' fasting blood sugar levels, triglycerides (TG), high density lipoprotein (HDL), hirsutism scores, blood pressure (systolic and diastolic), and waist circumference averaged 92, 60; 48.10; 96.90; 10.5; 121.5/77; 86.80, respectively, at baseline (pretreatment). After four months of treatment, the average levels of fasting blood sugar, triglycerides, high-density lipoproteins, blood pressure (systolic and diastolic), hirsutism scores, and waist circumference were 108.7, 50, 99.8, 7, 122.3, 82.7, and 87.50, respectively. Changes in lifestyle led to significant variations in fasting blood sugar levels as a metabolic parameter and hirsutism scores, but not in triglycerides, high-density lipoprotein, waist circumference, or blood pressure.
Downloads
References
Aulia, K. R. (2022). Anthropometric measurements and inflammatory marker in obese women. Jurnal Gizi Indonesia, 10(2): 88–94. https://doi.org/10.14710/jgi.10.2.88-94
Boyd, M., & Ziegler, J. (2019). Polycystic ovary syndrome, fertility, diet, and lifestyle modifications: A review of the current evidence. Topics in Clinical Nutrition, 34(1): 14–30. https://doi.org/10.1097/TIN.0000000000000161
Chen, W., & Pang, Y. (2021). Metabolic syndrome and PCOS: Pathogenesis and the role of metabolites. Metabolites, 11(12). https://doi.org/10.3390/metabo11120869
Elmenim, S. O. A., & Emam, A. M. M. (2016). Effect of lifestyle changes on symptoms of polycystic ovarian syndrome in obese girls. Journal of Nursing and Health Science, 5(3): 1–10. https://doi.org/10.9790/1959-0503020110
Khalid, S., Zia Shahid, M., Shahid, M., Naveed, M., Atif, M., Tufail, T., … Hussain, M. (2019). Nutritional and lifestyle modifications of polycystic ovary syndrome (pcos) in obesity. Researchgate.Net, 15(6): 259–272. https://doi.org/10.12692/ijb/15.6.259-272
Kim, C. H., & Lee, S. H. (2022). Effectiveness of lifestyle modification in polycystic ovary syndrome patients with obesity: A systematic review and meta-analysis. Life, 12(2). https://doi.org/10.3390/life12020308
Ortiz-Flores, A. E. (2019). Diagnosis of disorders of glucose tolerance in women with polycystic ovary syndrome (PCOS) at a tertiary care center: fasting plasma glucose or oral glucose tolerance test? Metabolism: Clinical and Experimental, 93:86–92. https://doi.org/10.1016/j.metabol.2019.01.015
Palomba, S. (2018). Infertility in women with polycystic ovary syndrome: Pathogenesis and management. Infertility in Women with Polycystic Ovary Syndrome: Pathogenesis and Management. https://doi.org/10.1007/978-3-319-45534-1
Sirait, B. I. (2018). Sindroma Ovarium Polikistik dan Infertilitas. Jurnal Ilmiah WIDYA, 5(3): 1–6. http://repository.uki.ac.id/id/eprint/1691%0Ahttp://inajog.com/index.php/journal/article/view/849
Stracquadanio, M., & Ciotta, L. (2015). Metabolic Aspects of PCOS. https://doi.org/10.1007/978-3-319-16760-2
Wu, C. H., Chiu, L. T., Chang, Y. J., Lee, C. I., Lee, M. S., Lee, T. H., & Wei, J. C. C. (2020). Hypertension risk in young women with polycystic ovary syndrome: A nationwide population-based cohort study. Frontiers in Medicine, 7(September): 1–9. https://doi.org/10.3389/fmed.2020.574651
Downloads
Published
Issue
Section
License
Journal Author(s) Rights
To publish and disseminate research articles, Sains Medika: Jurnal Kedokteran dan Kesehatan requires non-exclusive publishing rights (transferred from author(s) to publisher). This is determined by a publishing agreement between the Author(s) and Sains Med. J. Kedokt. dan Kesehat. This agreement governs with the transfer or license of the copyright of publishing to Sains Med. J. Kedokt. dan Kesehat, while Authors still retain significant rights to use and share their own published articles. Sains Med. J. Kedokt. dan Kesehat supports the need for authors to share, disseminate and maximize the impact of their research and these rights, in any databases.
As a journal Author, you have rights for a wide variety of uses of your article, including use by your institution or company of employment. These Author rights can be exercised without the need to obtain specific permission. Authors publishing in Sains Med. J. Kedokt. dan Kesehat have wide rights to use their works for teaching and scholarly purposes without needing to seek permission, including:
- Use for classroom teaching by Author or Author's institution and presentation at a meeting or conference and distributing copies to attendees;
- Use for internal training by author's company;
- Distribution to colleagues for their research use;
- Use in a subsequent compilation of the author's works;
- Inclusion in a thesis or dissertation;
- Reuse of portions or extracts from the article in other works (with full acknowledgement of final article);
- Preparation of derivative works (other than commercial purposes) (with full acknowledgement of final article);
- Voluntary posting on open web sites operated by author or author's institution for scholarly purposes,
Authors/Readers/Third Parties can copy and redistribute the material in any medium or format, as well as remix, transform, and build upon the material for any purpose, including commercial purposes, but they must give appropriate credit (the name of the creator and attribution parties (authors detail information), a copyright notice, an open access license notice, a disclaimer notice, and a link to the material), provide a link to the license, and indicate if changes were made (Publisher indicates the modification of the material (if any) and retain an indication of previous modifications using a CrossMark Policy and information about Erratum-Corrigendum notification).
Authors/Readers/Third Parties can read, print and download, redistribute or republish the article (e.g. display in a repository), translate the article, download for text and data mining purposes, reuse portions or extracts from the article in other works, sell or re-use for commercial purposes, remix, transform, or build upon the material, they must distribute their contributions under the same license as the original Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright Transfer Agreement for Publishing (Publishing Right)
The Authors submitting a manuscript do so on the understanding that if accepted for publication, the non-exclusive right for publishing (publishing right) of the article shall be assigned/transferred to the Publisher of Sains Medika: Jurnal Kedokteran dan Kesehatan and Faculty of Medicine Universitas Islam Sultan Agung (FK UNISSULA).
Upon acceptance of an article, authors will be required to complete a 'Copyright Transfer Agreement for Publishing (CTAP)'. An e-mail will be sent to the Corresponding Author confirming receipt of the manuscript together with a 'Copyright Transfer Agreement for Publishing' form by online version of this agreement.
Sains Medika: Jurnal Kedokteran dan Kesehatan and Faculty of Medicine Universitas Islam Sultan Agung (FK UNISSULA), the Editors and the Advisory International Editorial Board make every effort to ensure that incorrect or misleading data, opinions or statements be published in the journal. In any way, the contents of the articles and advertisements published in the Sains Medika: Jurnal Kedokteran dan Kesehatan are sole and exclusive responsibility of their respective authors and advertisers.
Remember, even though we ask for a transfer of copyright for publishing (CTAP), our journal Author(s) retain (or are granted back) significant scholarly rights as mentioned before.
The Copyright Transfer Agreement for Publishing (CTAP) Form can be downloaded here: [Copyright Transfer Agreement for Publishing (CTAP) Form Sains Medika 2022]
The copyright form must be electronically signed and emailed to the Editorial Office in the original form below:
Dr. Suparmi, S.Si, M.Si (ERT) (Editor-in-Chief)
Editorial Office of Sains Medika: Jurnal Kedokteran dan Kesehatan
Gedung Dekanat Lantai 1 Fakultas Kedokteran Universitas Islam Sultan Agung
Jl. Raya Kaligawe KM 4 Semarang 50112, Central Java, Indonesia
Telp/Whatsapp: +62 812-2993-3369
E-mail: sainsmedika@unissula.ac.id
(This policy statements has been updated 19 October 2022)
What is Crossmark?
CrossMark, a multi-publisher initiative from CrossRef, provides a standard way for readers to locate the authoritative version of a document. Sains Medika: Jurnal Kedokteran dan Kesehatan acknowledges the significance of the integrity and completeness of the scholarly record to scholars and librarians, and places the utmost importance on preserving the credibility of its electronic archive. Clicking on the CrossMark icon will inform the reader of a document's current status and may provide additional publication record information.





