Interleukin-6 (IL-6), Interleukin-8 (IL-8), and Tumor Necrosis FactorAlpha (TNF-a): Their Role in the Development and Metastasis of Tumor Cells

I Gede Angga Adnyana*  -  , Indonesia

(*) Corresponding Author

ABSTRACT: Cancer is a disease caused by uncontrolled and excessive cell division. The death caused by cancer is largely due to the cancer cell metastasis process. Cancer metastasis process is a consequence of molecules signaling pathways and interactions amongst cells in the body. Molecules involved and attributable to cancer metastasis are IL-6, IL-8, and TNF-α. This article aimed to describe the roles of IL-6, IL-8, and TNF-α in the process of various cancer cases.

Keywords: cancer, IL-6, IL-8, TNF-alpha, metastasis

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ISSN: 2339-093X (Online) | 2085-1545 (Print)
DOI : 10.30659/sainsmed

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