PERBANDINGAN JUMLAH ODONTOBLAST-LIKE CELLS PADA PULPA GIGI SETELAH APLIKASI TIGA JENIS MEDIKAMEN KAPING PULPA Studi Terhadap Tikus Putih (Rattus norvegicus) Galur Wistar

Abstract

Pulp capping is a treatment indicated for pulp that has a traumatic injury or caused by iatrogenic factors, by placing calcium hydroxide medicaments, Mineral Trioxide Aggregate (MTA), or Biodentine directly on the pulp, stimulating the formation of odontoblast-like cells. Odontoblast-like cells produced from undifferential mesenchyme cells after experiencing death. The objective of this research was to determine the effect of placing three pulp capping medicaments on the odontoblast-like cell numbers in  tooth pulp Rattus norvegicus. This research method used a true experimental laboratory post test only design, consisting of four groups and samples of 24 Wistar rats. The maxillary molar teeth 1 were prepared until bleeding happens. The three groups were given medicaments and all animal teeth were temporarily filled for 7 days. The tissues were made as histological slide by hematoxylin-eosin staining, and odontoblast-like cell counts were observed. Data analyzed by One Way Anova test and LSD Post Hoc. The results indicates some significant effect on the odontoblast-like cell numbers between on the of pulp medicaments  with negative control group.  There are no significant difference between the Biodentin and MTA groups there in the number of odontoblast-like cells.

Key words: odontoblast-like cells, calcium hydroxide, mineral trioxide aggregate, biodentine